cialis online purchase In our three substudies, we assessed plasma aldosterone, renin, and aldosterone to renin ratio ARR as predictors of home systolic blood pressure, and estimated prevalence of primary aldosteronism substudy 1; assessed the effects of each drug in terms of thoracic fluid index, cardiac index, stroke index, and systemic vascular resistance at seven sites with haemodynamic monitoring facilities substudy 2; and assessed the effect of amiloride 10 20 mg once daily on clinic systolic blood pressure during an optional 6 12 week open label runout phase substudy 3